Topical NSAIDs are better than placebo

Initial treatment of biliary colic: are NSAIDs better than opiates?

Patient A 45-year-old healthy male presents to urgent care clinic with acute right upper quadrant (RUQ) abdominal pain without fevers. The patient’s exam confirms a tender RUQ without rebound or guarding. He is found to have a white blood cell count of 15,000 with normal liver function and biliary tests. He is clinically diagnosed with biliary colic and an abdominal ultrasound is ordered to eva...

Cyclooxygenase (COX-2) selective inhibitors. Any better than NSAIDs?

Two Are Better than One?

This paper uses Markov-switching specifications to create a hybrid model with time-varying loading on each of chartist and fundamentalist approaches. The empirical data include the U.S. dollar exchange rates of four Asian tiger countries’ currencies including NTD, SGD, HKD and KOW from 1980 to 2000. Our empirical findings are consistent with the following notions. First, the forecasting perform...

Review: bisphosphonates are modestly better than placebo for relieving painful bone metastases.

M e t h o d s Data sources: 7 databases, scientific proceedings, and abstracts of professional associations. Study selection and assessment: Randomized controlled trials (RCTs) that included patients who had bone metastases with or without pain at enrollment, measured pain as an outcome, allowed antineoplastic therapy or rescue pain medications (if available to all patients), and compared bisph...

Review: anticonvulsants are better than placebo for reducing the frequency of migraine attacks.

and commentary also appear in ACP Journal Club. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . For correspondence: Dr E Chronicle, University of Hawaii at Manoa, Honolulu, HI, USA. [email protected] Source of funding: International Headache Society. Anticonvulsants v placebo for number of patients who responded with >5...